A: DNA transcription does not occur when chromatin is tight.
B: The future generation cells take information from chromatin modification.
C: Acetylation of histone tails in Chromatin helps DNA during transcription process.
D: Acetylation of histone tails is reversible.
E: Methylation of histone tails leads the condensation of chromatin.
F: Deacetylation of histone tails in chromatin loosens the association between nucleosomes and DNA.
Logically, all the options A, B, C, D, E and F are correct.
The correct answers are:
There is a reason why chromatic is thick and clusterous in the nucleus. The most general explanation is methylation of histone cells. Moreover, Chromatic itself is a complex combo of DNA and proteins, it helps producing and forming chromones in eukaryotic cells. Yes, the future cells do take information from the modified chromatin.
Since DNA can never appear in the shapes of linear strands. Therefore, chromatin is condensed so it can fit around the nuclear proteins that are present inside the nucleus. Chromosomes are inside histone proteins, usually in a thick form, and this structure overall refers to Chromatin. When the chromosomes are highly packed, the DNA can not transcribe properly the way it should.
Acetylation of histone tails can reverse itself and a catalyst HATs play an important role in that. It can change Acetyl to lysine K and HDACs cause the reversal of Acetylation.
Acetylation of histone cells affects the DNA transcription to a great extent. It can make the charge of the histone tail to go from positive to very neutral and so on. In general, it increases the traits and expression of genes that pass to the next generation cells during the transcription process. The gene info passed onto DNA when the transcription active and underway. However, HDAC can reverse the process, causing an opposite effect by leading to deacetylation which is also Acetylation reversal.
Chromatin and DNA transcription:
DNA is always present in the nucleus of eukaryotic cells. As we all are familiar with how it works, it takes on the gene traits and information, passes important genetic codes to the cells.
In eukaryotic cells, the DNA makes a combo with histones that are protein. When it makes a complex bond with the proteins, a structure forms is known as nucleosome.
The histrones forming the structure refer to Octamer. These proteins have names like H2B, H2A, H3, and H4. In other words, these four Atoms nucleus in a cluster form, not in linear strands. When the chromatic is fully packed with these proteins, it becomes heterochromatin. When it is light in weight, the protein bond breaks down, and the DNA gets access to gene transcription and information. It is a process of euchromatic in which DNA sequence is copied into mRNA stands.